The clinical usefulness of a histopathological study of the placenta at San Vicente de Paul Teaching Hospital

Authors

  • Hernán Cortés
  • Henry Muñoz

DOI:

https://doi.org/10.18597/rcog.500

Keywords:

placenta, pathology, chorangiosis, ischemia

Abstract

Objective: characterising placental findings regarding maternal or fetal pathology and ascertaining the percentage of pathological findings in the samples sent for study.

Materials and methods: this was a descriptive-retrospective study carried out at San Vicente de Paul teaching hospital. All placentas submitted to histological study during the last three years (2003-2005) were included. All the patients’ clinical histories were checked to establish histological diagnosis and the reason why placentas were sent for study (maternal or foetal complication).

Results: 60 placentas were checked; 19 (31.6%) were reported as being normal. The most prevalent characteristics were ischemic changes and amnionitis. Ischemic changes were most frequently found in cases of preeclampsia and intra-uterine growth retardation (IUGR). Amnionitis was found in cases of premature rupture of membranes (PRM), syphilis and premature labour. No findings were reported regarding foetal malformations.

Conclusions: just 1% of the placentas were sent for pathology, 68% of them presenting significant findings compared to other series where important changes were reported in 92% of them. Sending placentas having macroscopic abnormalities and those having maternal and foetal indications to pathology must be encouraged to increase ascertaining relevant findings.

Author Biographies

Hernán Cortés

Ginecólogo y obstetra. Universidad de Antioquia (UA), docente UA, ginecólogo Cooperativa SOGOS, Hospital Universitario San Vicente de Paúl. Medellín, Colombia.

Henry Muñoz

Residente de segundo año de Ginecología y Obstetricia. Universidad de Antioquia.

References

Altshuler G, Hyde SR. Clinicopathologic implications of placental pathology. Clin Obstet Gynecol 1996;39:549-70.

Altshuler G, Deppisch LM. College of American Pathologists Conference XIX on the Examination of the Placenta: report of the Working Group on Indications for Placental Examination. Arch Pathol Lab Med 1991;115:701-3.

Beebe LA, Cowan LD, Altshuler G. The epidemiology of placental features: associations with gestational age and neonatal outcome. Obstet Gynecol 1996;87:771-8.

Kaplan C, Lowell DM, Salafia C. College of American Pathologists Conference XIX on the Examination of the Placenta: report of the Working Group on the Definition of Structural Changes Associated with Abnormal Function in the Maternal/Fetal/Placental Unit in the Second and Third Trimesters. Arch Pathol Lab Med 1991;115:709-16.

Romero R, Mazor M, Morrotti R, Avila C, Oyarzun E, Insunza A, et al. Infection and labor. VII. Microbial invasion of the amniotic cavity in spontaneous rupture of membranes at term. Am J Obstet Gynecol 1992;166:129-33.

Altshuler G. A conceptual approach to placental pathology and pregnancy outcome. Semin Diag Pathol 1993;10:204-21.

Kaplan CG. Postpartum examination of the placenta. Clin Obstet Gynecol 1996;39:535-48.

How to Cite

1.
Cortés H, Muñoz H. The clinical usefulness of a histopathological study of the placenta at San Vicente de Paul Teaching Hospital. Rev. colomb. obstet. ginecol. [Internet]. 2007 Mar. 30 [cited 2024 May 17];58(1):60-4. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/500

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Published

2007-03-30
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