Systemic lupus erythematosus and complications during pregnancy

Authors

  • Alexander Díaz-Castro

DOI:

https://doi.org/10.18597/rcog.360

Keywords:

systemic lupus erythematosus, pregnancy, cervical carcinoma, preeclampsia

Abstract

Background: as systemic lupus erythematosus (SLE) is a common disease in young women and does not affect fertility cases may usually be found in which a woman can be both pregnant and suffer from this disease at the same time. Eventhough prognosis has improved, SLE should still be considered as a high risk disease and should be followed up by a multidisciplinary team enjoying excellent ongoing communication. This case presentation was aimed at reviewing maternal prognosis regarding base disease, gestation and the foetus.

Case summary: a 35-year-old woman suffering form SLE and chronic arterial hypertension was being managed for cervical cancer (HG-ISL). During her treatment she became pregnant, thereby complicating the foetus’ health and her own.

Conclusions: interdisciplinary teams should be promoted in Colombia in hospitals so that particular management can be established for each patient presenting this type of disease as well as time limits on waiting. A social support network must be made available allowing the mother and newborn to feel welcome and be managed together, since they form a single unit differently to other cases involving patients suffering from cancer and lupus.

Author Biography

Alexander Díaz-Castro

Médico cirujano, Universidad Pedagógica y Tecnológica de Colombia. (UPTC). Médico hospitalario y urgencias, Hospital Regional de Vélez. Vélez, Colombia

References

Ucar E. Lupus y embarazo. Servicio de reumatología: unidad de lupus y embarazo Hospital de Basurto, Bilbao; 2003.

Development of the pregnancy and labor in patient with systemic lupus erithematosus. Geska Gynecol; 2004.

Alijotas-Reig J, Ferrer-Raventos JC. Life-threatening bleeding, pregnancy and lupus anticoagulant: success after steroid and anticoagulant therapy. Am J Reprod Inmunol 2004;52:129-32.

Nossent HC, Swaak TJ. Systemic lupus erythematosus. VI. Analysis of the interrelationship with pregnancy. J Rheumatol 1990;17:771-6.

Fraga A, Mintz G, Orozco J. Sterility and fertility rates, fetal wastage and maternal morbidity in systemic lupus erythematosus. J Rheumatol 1974;1:293-8.

Petri M. Systemic lupus erythematosus and pregnancy. Rheum Dis Clin North Am 1994;20:87-118.

Ordi Ros J, Mauri Plana M. Lupus eritematoso y gestación. Unidad de investigación de enfermedades sistémicas, Hospital Universitario Valle d´Hebron. Presentado en el XXXVI Congreso de la Sociedad Española de Nefrología, 2006 Oct. 18-21. Revista de Nefrología Española 2006;26 Supl 6 Resumen 442003.

Lupus y embarazo: lupus neonatal y lactancia. Visitado en 2008 Ene 20.Disponible en: http://www.southmex.com.mx/fmxlupus/www/embarazo.html

Bankowski BJ. The John Hopkins manual of gynecology and obstetrics: Dept. of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2nd edition. Philadelphia: Lippincott Williams & Wilkins; 2002.

Cunningham FG, Williams JW. Williams obstetrics. 20th ed. Stamford, Conn.: Appleton & Lange; 1997.

Krabbeden I, Dekker GA.Pregnancy outcome in patients with history of recurrent spontaneous miscarriages and documented thrombophilias. Obstet Gynecol Invest 2004;57:127-31.

Breur JM, Visser GM, Kruize AA, Stoutenberck P, Meijboom EJ. Treatment of fetal heart block with maternal steroid theraphy: case report and review of the ultrasound. Obstet Gynecol 2004;24:467-72.

Moga Sampere I, Formiga Pérez F, Canet González R, Pac Ferraz M, Mitjavila Villero F, Fernández Nogués F. Embarazo y lupus eritematoso sistémico.Med Clin (Barc) 1993;101:530-3.

Urowitz MB, Gladman DD, Farewell VT, Stewart J, Mc Donald J. Lupus and pregnancy studies. Arthritis Rheum 1993;36:1392-7.

Tincani A, Faden D, Tarantini M, Lojacono A, Tanzi P, Gastaldi A, et al. Systemic lupus erythematosus and pregnancy: a prospective study. Clin Exp Rheumatol 1992;10:439-46.

Petri M, Allbritton J. Fetal outcome in lupus pregnancy: a retrospective case-control study of the Hopkins lupus cohort. J Rheumatol 1993;20:650-6.

Jungers P, Dougados M, Pélissier C, Kuttenn F, Lesavre P, Bach JF. Lupus nephropathy and pregnancy. Report of 104 cases in 36 patients. Arch Intern Med 1982;142:771-6.

Julkunen H, Jouhikainen T, Kaaja R, Leirisalo RM, Stephansson E, Palosuo T et al. Fetal outcome in lupus pregnancy: A retrospective case-control study of 242 pregnancies in 112 patients. Lupus 1993;2:125-31.

Minakami H, Idei S, Koike T, Tamada T, Yasuda Y, Hirota N. Active lupus and preeclampsia: a life threatening combination. J Rheumatol 1994;21:1562-3.

Mintz G, Niz J, Gutiérrez G, García-Alonso A, Karchmer S. Prospective study of pregnancy in systemic lupus erythematosus. Results of a multidisciplinary approach. J Rheumatol 1986;13:732-9.

Estes D, Larson DL. Systemic lupus erythematosus and pregnancy. Clin Obstet Gynecol 1965;8:307-21.

Pistiner M, Wallace DJ, Nessim S, Metzger AL, Klinenbert JR. Lupus erythematosus in the 1980s: a survey of 570 patients. Semin Arthritis Rheum 1991;212:55-64.

Le Huong D, Wechsler B, Vauthier-Brouzes D, Seebacher J, Lefèvebre G, Bletry O, et al. Outcome planned pregnancies in systemiclupus erythematosus: a prospective study on 62 pregnancies. Br J Rheumatol 1997;36:772-7.

Carmona F, Font J, Cervera R, Muñoz F, Cararach V, Balasch J. Obstetrical outcome of pregnancy in patients with systemic lupus erythematosus. A study of 60 cases. Eur J Obstet Gynecol Reprod Biol 1999;83:137-42.

Mascola MA, Repke JT. Obstetric management of the high-risk lupus pregnancy. Rheum Dis Clin North Am 1997;22:119-32.

How to Cite

1.
Díaz-Castro A. Systemic lupus erythematosus and complications during pregnancy. Rev. colomb. obstet. ginecol. [Internet]. 2009 Mar. 30 [cited 2024 May 17];60(1):93-9. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/360

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2009-03-30
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