Progestin only-oral contraceptives

Authors

  • Alvaro Monterrosa

DOI:

https://doi.org/10.18597/rcog.536

Keywords:

mini pill, contraception, contraceptives, oral, progestins, progestin-only contraceptives, progestagens

Abstract

Although progestin-only oral contraceptives or mini-pills have been available for many years, they are less known and less prescribed or recommended than combined oral contraceptives. Due to being oestrogen-free, progestin-only oral contraceptives have an important role and a defined place in contemporary hormonal contraception. The first progestin mini-pills (ethynodiol, linestrenol and norethisterone) were followed by levonorgestrel and then desogestrel; drospirenone is now being evaluated. The levonorgestrel mini-pill has always had a unique place in oral contraception whilst breastfeeding; the desogestrel mini-pill may also be recommended beyond the breastfeeding period due to its ovulation-inhibiting ability. Such ability has also been observed when prescribing drospirenone-only pills. The purpose of this review is to orientate people working in the area of health to identify the differences and similarities between the mini-pill and combined oral contraceptives. Progestin-only oral contraceptives must be considered during contraceptive counselling to ensure good clinical safety and because of the observed benefits.

Author Biography

Alvaro Monterrosa

Profesor Titular, Jefe de la Sección de Subespecialidades, Departamento de Ginecología y Obstetricia Facultad de Medicina Universidad de Cartagena. Coordinador de Investigaciones Universidad del Sinú Seccional Cartagena. Cartagena, Colombia. Correo electrónico: alvaromonterrosa@gmail.com

References

Collaborative Study Group on the Desogestrel containing Progestogen only Pill. A double-blind study comparing the contraceptive efficacy, acceptability and safety of two progestogen-only pills containing desogestrel 75 micrograms/day or levonorgestrel 30 micrograms/day. Eur J Contracept Reprod Health Care 1998;3:169–78.

Edwards L. An update and oral contraceptive options. Formulary. 2004;39:104–21.

Winkler UH, Howie H, Buhler K, Korver T, Geurts TB, Coelingh Benningk HJ. A Randomized controlled double blind study of the effects on hemostasis of two progestogen-only pills containing 75 microgram desogestrel or 30 microgram levonorgestrel. Contraception 1998;57:385–92.

Hussain SF. Progestogen-only pills and high blood pressure: is there an association? A literature review. Contraception 2004;69:89–97.

McCann MF, Potter LS. Progestin only contraception: a comprehensive review. Contraception 1994;50: S1–195.

Winkler UH. Effects on hemostatic variables of desogestrel and gestodene containing oral contraceptives in comparison with levonorgestrel containing oral contraceptives: a review. Am J Obstet Gynecol 1998;179:S51-61.

Newton J. Classification and comparison of oral contraceptives containing new generation progestogens. Hum Reprod Update 1995; 1:231–63.

Broome M, Fotherby K. Clinical experiences with the progestogen only pill. Contraception 1990;42:489–95.

WHO. Medical eligibility criteria for contraceptive use. Third edition; 2004.

Monterrosa A. Anticoncepción oral en perspectiva. Primera edición. Editorial la Popa; 2005.

Korver T, Klipping CH, Hegar-Mahn D, Duijkers I, van Osta G, Dieben T. Maintenance of ovulation inhibition with the 75 microgram desogestrel-only contraceptive pill (Cerazette) after scheduled 12-h delays in tablet intake. Contraception 2005;71:8–13.

Rice CF, Killick SR, Dieben T, Ovulation inhibition by two progestogens: desogestrel and Levonorgestrel. Br J Obstet Gynaecol 1998;105(suppl 17):41.

Monterrosa A. Anticonceptivos orales combinados. Tercera edición. Bogotá: Editorial Impresos Calidad; 2003.

Rosenbaum P, Schmidt W, Helmerhorst FM, Wutte W, Rossmanith W, Freundl F, et al. Inhibition of ovulation by a novel progestogen (drospirenone) alone or in combination with ethinylestradiol. Eur J Contracept Reprod Health Care 2000;5:16-24.

How to Cite

1.
Monterrosa A. Progestin only-oral contraceptives. Rev. colomb. obstet. ginecol. [Internet]. 2006 Mar. 30 [cited 2024 May 18];57(1):45-53. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/536

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Published

2006-03-30

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Review Article
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