The prevalence of ampicillin resistance in pregnant women suffering from urinary tract infections in the San José Teaching Hospital. Popayán, Colombia 2007-2008
DOI:
https://doi.org/10.18597/rcog.316Keywords:
urinary infection, pregnancy, ampicillinAbstract
Introduction: urinary tract infection is the most frequently occurring infectious complication of pregnancy; it affects 20% to 30% of all pregnancies. Its relationship with pre-term childbirth, premature membrane rupture and low birth-weight has been clearly documented and, inspite of the development of new antibiotics, it continues being associated with high maternal and foetal morbidity and mortality. This article tries to determine the prevalence of ampicillin resistance in pregnant women suffering from urinary tract infection, this being especially important if ampicillin continues being the antibiotic of choice for treating this condition.
Methodology: a descriptive prospective study was made in the San José teaching hospital (Popayán) between January 2007 and December 2008. It involved 50 pregnant women having a positive urine culture and ampicillin sensidisc in the antibiogram.
Results: the prevalence of ampicillin resistance was 58%, similar to that stated in previous studies, thereby showing a high microorganism ampicillin resistance rate. No resistance to ceftazidime, ceftriaxone or cefotaxime was found; low resistance to nitrofurantoin, amoxicillin-clavulanate, gentamycin and cephalexin was reported.
Conclusions: using ampicillin as the antibiotic of choice in pregnant women suffering from urinary tract infection is no longer recommended; the resistance rate found (58%) greatly exceeds the maximum limit recommended by experts (20%).
Author Biographies
Rodolfo L. Casas-P.
Manuelita Ortiz
Darío Erazo-Bucheli
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