Urinary infection during pregnancy: a profile of resistance to treatment in the General Hospital in Neiva, Colombia

Authors

  • Fidel Ernesto Ferreira
  • Sandra Ximena Olaya
  • Pedro Zúñiga
  • Mónica Angulo

DOI:

https://doi.org/10.18597/rcog.532

Keywords:

urinary tract infections, pregnancy, resistance, ampicillin, Colombia

Abstract

Urinary tract infections are frequent during pregnancy. Escherichia coli is the most common pathogen, followed by Klebsiella pneumoniae, different types of EnterobacterStreptococcus andStaphylococcus. Ampicillin has been used as first choice antibiotic, but there is high bacterial resistance to it.

Objective: to determine the level of resistance to antibiotics of the germs most frequently involved in urinary tract infection during pregnancy.

Methodology: results of urine cultures and antibiotic sensitivity studies performed on pregnant women in a period of 15 months from January 2004 to April 2005 were revised.

Results: a total of 45 patients had positive urine cultures. Escherichia coli was the pathogen more frequently found (64% of the cultures), followed by Klebsiella pneumoniae. The resistance of Escherichia coli to ampicillin was 82% and to gentamicin 3%.

Author Biographies

Fidel Ernesto Ferreira

Ginecoobstetra, Universidad del Rosario, especialista en medicina materno fetal Universidad Católica de Chile, Jefe de medicina materno fetal, Hospital Universitario Hernando Moncaleano Perdomo de Neiva, Docente de la Universidad Surcolombiana, Neiva (Huila)

Sandra Ximena Olaya

Residente de III año de Ginecología y Obstetricia, Universidad Surcolombiana. 

Pedro Zúñiga

Médico Patólogo, Universidad del Valle; Jefe del Laboratorio Clínico Hospital Universitario Hernando Moncaleano Perdomo de Neiva.

Mónica Angulo

Residente de I año de Ginecología y Obstetricia, Universidad Surcolombiana.

References

Hootson TM. Recurrent urinary tract infection in women. Int J Antimicrob Agents 2001;17:259-68.

Navas-Nacher EL, Dardick F, Venegas MF, Anderson BE, Schaeffer AJ, Duncan JL. Relatedness of Escherichia coli colonizing women longitudinally. Mol Urol 2001;5:31-6.

Kunin CM. Urinary tract infections in females.Clin Infect Dis 1994;18:11-2.

Ovalle A, Martínez MA, Wolf M, Cona E, Valderrama O, Villablanca E, et al. Estudio prospectivo randomizado comparativo de la eficacia, seguridad y costos de la cefuroxima versus cefradina en pielonefritis aguda en el embarazo. Rev Méd Chile 2000; 128:749-57.

Nicolle LE. Urinary tract infection: traditional pharmacologic therapies. Am J Med 2002;113 Suppl 1A:35S-44S.

González P, Correa R, Montiel F, et al. Tratamiento de las infecciones urinarias durante el embarazo, experiencia en pacientes. Rev Méd Chile 1988; 116:895-900.

Sobel JD. Pathogenesis of urinary tract infection. Role of host defenses. Infect Dis Clin North Am 1997;11:531-49.

Gilstrap LC 3rd, Ramin SM. Urinary tract infections during pregnancy. Obstet Gynecol Clin North Am 2001;28:581-91.

Romero R, Oyarzun E, Mazor M, Sirtori M, Hobbins JC, Bracken M. Meta-analysis of the relationship between asymptomatic bacteriuria and preterm delivery low birth weight. Obstet Gynecol 1989;73:576-82.

Van Dorsten J, Lenke RR, Schifrin BS. Pyelonephritis in pregnancy. The role of in hospital management and nitrofurantoin suppression. J Reprod Med 1987;32:895-900.

Naber KG. Experience with the new guidelines on evaluation of new anti-infective drugs for the treatment of urinary tract infections. Int J Antimicrob Agents 1999;11:189-96.

Pinto E. Antimicrobial agents resistance in Chile nowadays. Rev Chil Infectol 2002; 19 Suppl 3:S213-S218.

Speller DC. The clinical impact of antibiotic resistance. J Antimicrob Chemother 1988;22:583-6.

OMS. Contengamos la resistencia bacteriana. Informe de la OMS sobre enfermedades infecciosas 2000. Madrid: Ed. Ministerio de Sanidad y Consumo; 2001. p.1-10.

Gerding DN, Martone WJ. SHEA conference on antimicrobial resistance. Infect Control Hosp Epidemiol 2000;21:347-51.

Barza M, Ioannidis J, Cappelleri JC, Lau J. Single or multiple daily doses of aminoglycosides: a meta-analysis. BMJ 1996;312-338-45.

Abarzua F, Zajer C, Donoso B, Belmar J, Riveros JP, González P y cols. Reevaluación de la sensibilidad antimicrobiana de los patógenos urinarios en el embarazo. Rev Chil Obstet Ginecol 2002;67:226-31.

Sussman O. Saravia J. Estudio comparativo de la eficacia de la dosis única de ofloxacina, amoxacilina y amoxacilina clavulanato. Hospital San Juan de Dios -Santa Fe de Bogotá 1992. Revista CES Medicina 1993;7:179-81.

Rossi A, Tokumoto M, Galas M, Soloaga R, Corso A y red nacional de laboratorios que participan en el programa WHONET. Vigilancia de la resistencia a los antibacterianos en Argentina. Programa WHONET, 1995-1996. Rev Panam Salud Pública 1999;6:234-41.

Khan A, Das SC, Ramamurthy T, Sikdar A, Khanam J, Yamasaki S, et al. Antibiotic resistance, virulence gene, and molecular profiles of Shiga toxin-producing Escherichia coli isolates from diverse sources in Calcutta, India. J Clin Microbiol. 2002;40:2009-15.

How to Cite

1.
Ferreira FE, Olaya SX, Zúñiga P, Angulo M. Urinary infection during pregnancy: a profile of resistance to treatment in the General Hospital in Neiva, Colombia. Rev. colomb. obstet. ginecol. [Internet]. 2005 Sep. 9 [cited 2024 Jul. 2];56(3):239-43. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/532

Downloads

Download data is not yet available.

Published

2005-09-09
QR Code

Altmetric

Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views

Some similar items: