Obstetric complications after a radical trachelectomy: case report and review of literature

Authors

  • María de la Calle Fernández-Miranda
  • José Ángel García-Hernández
  • Ramón Usandizaga Elio
  • Javier de Santiago García
  • Fernando Magdaleno Dans
  • Antonio González-González

DOI:

https://doi.org/10.18597/rcog.273

Keywords:

cervical cancer, radical trachelectomy, pregnancy, obstetric complications

Abstract

Introduction: radical trachelectomy (TR) is a surgical technique which is used in the early stages of cervical cancer in females wishing to conserve their reproductive ability. Pregnancies following this surgical technique having been applied could trigger obstetric complications. This article was thus aimed at reviewing the literature related to these patients’ obstetric prognosis.

Methodology: a clinical case is presented. A literature search was made in MEDLInE databases, via PubMed and Cochrane, using the following key words: “cervical cancer”, “radical trachelectomy”, “pregnancy”, “obstetric complications”.

Results: 17 articles were evaluated, covering review articles, articles expressing opinion and clinical cases.

Conclusion: preserving fertility in early stages of cervical cancer by radical trachelectomy is increasingly acquiring more acceptance as more cases are published in the literature. Obstetric results seem to be becoming more favorable even though complications are becoming more numerous compared to incidence in the general population.

Author Biographies

María de la Calle Fernández-Miranda

Profesor Asociado, Facultad de Medicina, Universidad Autónoma de Madrid. Unidad de Tocología de Alto Riesgo del Servicio de Obstetricia y Ginecología, Hospital La Paz. Madrid (España).

José Ángel García-Hernández

Residente de cuarto curso, Servicio de Obstetricia y Ginecología, Hospital La Paz. Madrid (España).

 

Ramón Usandizaga Elio

Profesor Titular, Facultad de Medicina, Universidad Autónoma de Madrid. Jefe de Sección, Unidad de Suelo Pélvico del Servicio de Obstetricia y Ginecología, Hospital La Paz. Madrid (España).

 

Javier de Santiago García

Profesor Asociado, Facultad de Medicina, Universidad Autónoma de Madrid. Jefe de Servicio de Ginecología Oncológica y de Quirófano de Ginecología, Hospital La Paz. Madrid (España).

 

Fernando Magdaleno Dans

Profesor Asociado, Facultad de Medicina, Universidad Autónoma de Madrid. Jefe de Sección de paritorio del Servicio de Obstetricia y Ginecología, Hospital La Paz. Madrid (España).

 

Antonio González-González

Catedrático, Facultad de Medicina, Universidad Autónoma de Madrid. Jefe de Servicio de Obstetricia y Ginecología, Hospital La Paz. Madrid (España).

 

References

Parkin DM, Bray F, Ferlay J, Pisani P. Global Cancer Statistics, 2002. CA Cancer J Clin 2005;55:74-108.

Burnett AF. Radical trachelectomy with laparoscopic lymphadenectomy: review of oncologic and obstetrical outcomes. Curr Opin Obstet Gynecol 2006;18:8-13.

Sonoda Y, Abu-Rustum nR, Gemignani ML, Chi DS, Brown CL, Poynor EA, et al. A fertility-sparing alternative to radical histerectomy: how many patients may be eligible? Curr Opin Oncol 2004;95:534-8.

Dargent D, Brun JL, Roy M, Remy I. Pregnancies following radical trachelectomy for invasive cervical cancer. Gynecol Oncol 1994;52:105.

Plante M. Vaginal radical trachelectomy: an update. Gynecol Oncol 2008;111:S105-10.

Ramírez PT, Schmeler KM, Soliman PT, Frumovitz M. Fertility preservation in patients with early cervical cancer: Radical trachelectomy. Gynecol Oncol 2008;110:S25-8.

Gien LT, Covens A. Fertilty-sparing options for early stage cervical cancer. Gynecol Oncol 2010;117:350-2.

Beiner ME, Covens A. Surgery insight: radical vaginal trachelectomy as a method of fertility preservation for cervical cancer. Nat Clin Pract Oncol 2007;4:353-61.

Boss EA, van Golde RJ, Beerendonk CC, Massuger LF. Pregnancy alter radical trachelectomy: a real option? Gynecol Oncol 2005;99:S152-6.

Jolley JA, Battista L, Wing DA. Management of pregnancy after radical trachelectomy: case reports and systematic review of literature. Am J Perinatol 2007;24:531-9.

Plante M, Renaud MC, François H, Roy M. Vaginal radical trachelectomy: an oncollogically safe fertility-preserving surgery. An updated surgery of 72 cases and review of the literature. Gynecol Oncol 2004;94:614-23.

Schlaerth JB, Sitos nM, Schlaerth AC. Radical trachelectomy and pelvic lymphadenectomy with uterine preservation in the treatment of cervical cancer. Am J Obstet Gynecol 2003;188:29-34.

Ungár L, Pálfalvi L, Hogg R, Siklós P, Boyle DC, Del Priore G, et al. Abdominal radical trachelectomy: a fertility-preserving option for women with early cervical cancer. BJOG 2005;112:366-9.

Olawaiye A, Del Carmen M, Tambouret R, Goodman A, Fuller A, Duska LR. Abdominal radical trachelectomy: success and pitfalls in a general gynecologic oncology practice. Gynecol Oncol 2009;112:506-10.

Petignat P, Stan C, Megevand E, Dargent D. Pregnancy after trachelectomy: a high risk condition of preterm delivery. Report of a case and review of the literature. Gynecol Oncol 2004;94:575-7.

Shepherd JH, Mould T, Oram DH. Radical trachelectomy in early stage carcinoma of the cervix: outcome as judged by recurrence and fertility rates. BJOG 2001;108: 882-5.

Bernardini M, Barret J, Seaward G, Covens A. Pregnancy outcome in patients after radical trachelectomy. Am J Obstet Gynecol 2003;189:1378-82.

How to Cite

1.
Fernández-Miranda M de la C, García-Hernández J Ángel, Elio RU, García J de S, Dans FM, González-González A. Obstetric complications after a radical trachelectomy: case report and review of literature. Rev. colomb. obstet. ginecol. [Internet]. 2010 Sep. 30 [cited 2024 May 19];61(3):262-6. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/273

Downloads

Download data is not yet available.

Published

2010-09-30
QR Code

Altmetric

Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views
Crossref Cited-by logo

Some similar items: