Degeneración sarcomatosa rápida de un leiomioma simplástico pleomórfico de útero, reporte de caso y revisión de la literatura
DOI:
https://doi.org/10.18597/rcog.410Palabras clave:
leiomioma, leiomiosarcoma, menorragia, sepsisResumen
Objetivo: revisar la epidemiología y el cuadro histopatológico de los sarcomas uterinos.
Presentación del caso: mujer de 35 años de edad atendida en el Hospital General de Medellín (Hospital de 3er nivel de atención, público, centro de referencia Obstétrica), por sangrado genital. Presentaba anemia y masa pélvica, que en el estudio histopatológico mostró como leiomiosarcoma uterino de alto grado.
Discusión: se describe como una lesión tumoral benigna atípica con celularidad variable, degenera en una lesión leiomiosarcoma de comportamiento agresivo, con intervalo de ataques de síntomas en fase temprana.
Biografía del autor/a
Oscar Alejandro Bonilla-Sepúlveda
Jaime Díaz-Cardona
Álvaro Restrepo-Pareja
Referencias bibliográficas
Persaud V. Arjoon PD. Uterine leiomyoma. Incidence of degenerative change and a correlation of associated symptoms. Obstet Gynecol 1970;35:432-6.
Razafintsalama T, Leveque J, Le Gall F, Paumier V, Pangui E, Kerisit J et al. Léiomyosarcome utérin. À propos de 9 observations et revue de la littérature. J Gynecol Obstet Biol Reprod 1997;26:256-62.
Benangiano G, Kivinen ST, Fadini R, Cronjé H, Klintorp S, van der Spuy ZM. Zoladex (goserelin acetate) and anemic patient: results of a multicentre fibroid study. Fertil Steril 1996;66:223-8.
Rein MS, Barbieri RL, Friedman AJ. Progesterone: A critical role in pathogenesis of uterine myomas. Am J Obstet Gynecol 1995;172:14-8.
Smith SK. The regulation of fibroid growth: time for a rethink? Br J Obstet Gynaecol 1993;100:977-9.
Oláh KS, Dunn JA, Gee H. Leiomyosarcomas have a poorer prognosis than mixed mesodermal tumours when adjusting for known prognostic factors: the result of a retrospective study of 423 cases of uterine sarcoma. Br J Obstet Gynaecol 1992;99:590-4.
Nordal RR, Thoresen SO. Uterine sarcomas in Norway 1956-1962: incidence, survival and mortality. Eur J Cancer 1997;33:907-11.
Harlow BL, Weiss NS, Lofton S. The epidemiology of sarcomas of the uterus. J Natl Cancer Inst 1986;76:399-402.
Hoskins WJ, Pérez CA, Young RC. Principles and practice of gynecologic oncology. 3rd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2001.
Brooks SE, Zhan M, Cote T, Baquet CR. Surveillance, epidemiology, and end results analysis of 2677 cases of uterine sarcoma 1989-1999. Gynecol Oncol 2004;93:204-8.
Leibsohn S, d'Ablaing G, Mishell DR Jr, Schlaerth JB. Leiomyosarcoma in a series of hysterectomies performed for presumed uterine leiomyosarcoma. Am J Obstet Gynecol 1990;162:968-76.
Umesaki N, Tanaka T, Miyama M, Kawamura N, Ogita S, Kawade J, et al. Positron emission tomography with (18) fluorodeoxyglucose of uterine sarcoma: a comparison with magnetic resonance imaging and power Doppler imaging. Gynecol Oncol 2001;80:372-7.
Fuller A Jr, Patterson D, Shimm D. Sarcomas of the female genital tract. En: Raaf J, ed. Soft tissue sarcomas: diagnosis and treatment. St. Louis, MO: Mosby; 1993. p. 187-200.
SchwartzLB, Diamond MP, Schwartz PE. Leiomyosarcomas: clinical presentation. Am J Obstet Gynecol 1993;168:180-3.
Forney JP, Buschbaum HJ.Classifying, staging, and treating uterine sarcomas. Contemp Ob Gyn 1981;18:47-69.
Poulsen HE, Taylor CW, Sobin LH, eds. Histological Typing of female genital tract tumours. Geneve: World Health Organization; 1975. p. 13.
Major FJ, Blessing JA, Silverberg SG, Morrow CP, Creasman WT, Currie JL, et al. Prognostic factors in early-stage uterine sarcoma: a Gynecologic Oncology Group study. Cancer 1993;71:1702-9.
Oda K, Okada S, Nei T, Shirai T, Takahashi M, Sano Y, et al. Cytodiagnostic problems in uterine sarcoma. Analysis according to a novel classification of tumor growth types. Acta Cytol 2004;48:181-6.
Omura GA, Major FJ, Blessing JA, Sedlacek TV, Thigpen JT, Creasman WT, et al. A randomized study of adriamycin with and without dimethyl triazenoimidazole carboxamide in advanced uterine sarcomas. Cancer 1983;52:626-32.
Evans HL, Chawla SP, Simpson C, Flinn KP. Smooth muscle neoplasms of the uterus other than ordinary leiomyoma. A study of 46 cases, with emphasis on diagnostic criteria and prognostic factors. Cancer 1988;62:2239-47.
Christopherson WM, Williamson EO, Gray LA. Leiomyosarcoma of the uterus. Cancer 1972;29:1512-7.
Cómo citar
Descargas
Descargas
Publicado
Número
Sección
| Estadísticas de artículo | |
|---|---|
| Vistas de resúmenes | |
| Vistas de PDF | |
| Descargas de PDF | |
| Vistas de HTML | |
| Otras vistas | |
