Cervical length measurement of 25 mm or less than for delivery identification within seven days in patients under threat of premature birth. Retrospective cohort study in a level IV hospital in Medellín, Colombia, 2009-2012
DOI:
https://doi.org/10.18597/rcog.59Keywords:
Premature labour, premature birth, cervical length measurement, predictionAbstract
Objective: To identify a cut-off point in women under threat of preterm birth with cervical length of 25 mm or less in order to improve delivery prediction within 7 days of the test.
Materials and methods: Retrospective cohort study in women with a single pregnancy between 24 and 36+6 weeks of gestation, diagnosed with threat of premature delivery and cervical length of 25 mm or less on admission. Patients in active labour or with premature membrane rupture, a history of cerclage or prior treatment with progesterone were excluded. Measurements were divided into range categories: 0 to 5, 6 to 10, 11 to 15, 16 to 20 and 21 to 25 mm, and birth prediction was compared with the presence or absence of birth within 7 days of the test. The likelihood ratio for each category and the area under the curve were estimated.
Results: The median latency period for delivery was 3 weeks (range 1-5). For the different cut-off points, the probability quotients for going into labour before seven days after the measurement were 3.3, 1.4, 1,3, 0.7 and 0.2, respectively. The area under the curve (AUC) for delivery at seven days was 0.711.
Conclusion: In women with cervical length under 25 mm and with a threat of preterm delivery, no cut-off point was found to help identify a greater or lesser risk of premature delivery.
Author Biographies
Sandra Janneth Lozano-Mosquera
Diana Lucía Muñoz-Pérez
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