Cyclopia: a report of 4 cases born during a 170-day period in the Valle Teaching Hospital in Cali, Colombia

Authors

  • Wilmar Saldarriaga
  • Carolina Isaza
  • Pierpaolo Mastroiacovo
  • Eduardo E. Castilla

DOI:

https://doi.org/10.18597/rcog.502

Keywords:

cyclopia, holoprosencephaly, congenital malformation

Abstract

Cyclopia is a rare congenital malformation which is non-compatible with life. It has heterogeneous aetiology and is characterised by the presence of a single eye in a central position, being secondary to alobar holoprosencephaly and having 1–3 prevalence per 100,000 births.

4 cases of cyclopia occurred in 3,594 births at the Valle teaching hospital in Cali, Colombia, from Dec 4th 2004 to May 23rd 2005. This represents an incidence of 1.11 cases per 1,000 births, being 50 times greater than that reported in the literature.

Author Biographies

Wilmar Saldarriaga

 Ginecólogo y obstetra. MSc en Ciencias Básicas Médicas. Profesor del Departamento de Morfología, Departamento de Ginecología y Obstetricia, Facultad de Salud, Universidad del Valle. Hospital Universitario del Calle. Fundación Clínica Valle del Lili. (Cali, Colombia).

Carolina Isaza

Profesora titular, Departamento de Morfología, Facultad de Salud, Universidad del Valle (Cali, Colombia)

Pierpaolo Mastroiacovo

Director, International Centre for Birth Defects of the International Clearinghouse for Birth Defects Monitoring Systems, Roma, Italia.

Eduardo E. Castilla

Coordinador del Estudio Colaborativo Latino Americano de Malformaciones Congénitas (ECLAMC), Instituto Oswaldo Cruz, Rio de Janeiro, Brasil, y Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina.

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How to Cite

1.
Saldarriaga W, Isaza C, Mastroiacovo P, Castilla EE. Cyclopia: a report of 4 cases born during a 170-day period in the Valle Teaching Hospital in Cali, Colombia. Rev. colomb. obstet. ginecol. [Internet]. 2007 Mar. 30 [cited 2024 May 19];58(1):70-7. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/502

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Published

2007-03-30
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