The influence of sperm DNA fragmentation on assisted reproduction techniques and embryo quality
DOI:
https://doi.org/10.18597/rcog.285Keywords:
DNA fragmentation, male infertility, embryo quality, assisted reproduction techniques (ART)Abstract
Objective: presenting a review of the literature about sperm DNA fragmentation, its impact on assisted reproduction techniques and embryo quality.
Methodology: the MEDLINE/PubMed database was searched; the search terms used were: sperm fragmentation, semen parameters, assisted reproduction techniques and embryo quality. Articles published from 1999 to 2010 were reviewed.
Results: sperm fragmentation studies provided complementary information about a patient’s sperm quality, this being a parallel test to semen analysis. Such tests’ diagnoses represent the starting point for taking decisions about the reproduction technique to be used.
Conclusion: the sperm ADN fragmentation index represents a valuable tool for ascertaining a patient’s fertilising ability.
Author Biographies
Alfredo Góngora-Rodríguez
Centro de Fertilidad Humana en México. México D.F. (México).
Diana Fontanilla-Ramírez
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Copyright (c) 2010 Revista Colombiana de Obstetricia y Ginecología
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