The new oral contraceptive of ultra low dose
DOI:
https://doi.org/10.18597/rcog.726Keywords:
Oral contraceptive, gestodene, ethinyl estradiol, pill-free interval, ultra low doseAbstract
From the introduction and massive use at world level of the pill in the decade of the sixty, it has been generated a growing heap of information related to its benefits, adverse effects and risks.
Product of that knowledge has been come carrying out a continuous decrease in the concentration of the estrogen, what has generated the establishment of a classification according to the concentration of the ethinyl estradiol. We have macrodosis, microdosis, very low dose and now ultra low dose. In turn the gestagens for their androgenic intrinsic property produces lipidics and vascular alterations, reason why the older compounds have opened the way to newer neuter molecules.
Those two strategies in the handling of the estrogen and the gestagen have allowed to diminish the cardiovascular risks and especially the thromboembolics. Since it is important to maintain the birth-control effectiveness, other regimes like the three-phase have been proposed.
The new pill of ultra low dose provides the smallest hormonal quantity until the present time. Ethinyl estradiol combination 15 ug more 60 ug of gestodene is the first one available; it has a higher amenorrhea, hypomenorhrea, and intermenstrual bleed rate than other pills of more hormonal concentration, and it should be administered at the novel regime of 24 days continuous and 4 days free.
Author Biography
Álvaro Monterrosa Castro
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