Cervical pathology and reporting of atypical squamous cells of undetermined significance (ASCUS) in cervical cytology

Authors

  • Mario Arturo González Mariño

DOI:

https://doi.org/10.18597/rcog.582

Keywords:

ASCUS, cytology, cervix

Abstract

Objective: To evaluate the relationship between the cervical pathology and the report of ASCUS (Atypical Squamus Cells of Undetermined Significance) pap in patients from the Liga Contra el Cáncer. Bogotá, Colombia.

Methods: This is an observational study of the type of case report. The ASCUS pap smear in the cytologic report of patients with a pathologic diagnosis of coilocitic atypia, condyloma, cervical intraepithelial neoplasia (CIN) I,II,III or invasive carcinoma was chosen to make the analysis by using the EPI INFO program.

Results: The ASCUS pap were found in 51(13.6%) out of the 374 pathologic reports selected to be analyzed. In 8 patients previous cervical treatments were undertaken. The biopsy report was coilocytic atypia or condiloma in 31 women, CIN I in 10, CIN II-III in 9 and a biopsy suggestive of adenosquamous neoplasm. An additional information favored a human papilloma lesion in 6 pap reports but a high-grade intraepithelial neoplasm was found in two biopsies. Personal and clinical information is shown.

Conclusions: The ASCUS pap involve a range from benign alterations, which are the majority, as well as the possibility of finding a neoplasm so that its report should no be underestimated. The Bethesda 2001 recommendations should select the patients needed of an active treatment. New research is needed on the utility of this classification.

Author Biography

Mario Arturo González Mariño

Médico Ginecólogo Oncólogo. e-mail: marioar90@hotmail.com

References

Bernard-Pearl L, Smith-McCune K. Controversies in the Management of ASCUS and AGCUS: Two very different beasts. Curr Probl Obstet Gynecol Fertil 2001; 24:7-23.

Jones HW. Clinical treatment of women with atypical squamous cells of undetermined significance or atypical glandular cells of undetermined significance cervical cytology. Clin Obstet Gynecol 2000;43:381-93.

Solomon D, Schiffman M, Tarone R, for the ALTS group. Comparison of three management strategies for patients with atypical squamous cells of undermined significance: baseline results from a randomized trial. J Natl Cancer Inst. 2001;93:293-9.

Wilkinson EJ. Pap smears and screening for cervical neoplasia. Clinical Obstetrics and Gynecology 1990;33:817-25.

Solomon D, Frable WJ, Vooijs GP, Wilbur DC et al. ASCUS and AGUS criteria. Acta Cytologica 1998;42:16-24.

Kurman RJ, Henson DE, Herbst AL, Noller KL, Schiffman M. Interim guidelines for management of abnormal cervical cytology. JAMA 1994;271: 1866-9.

Lachman MF, Cavallo-Calvanese C. Qualification of atypical squamous cells of undetermined significance in an independent laboratory: is it useful or significant? Am J Obstet Gynecol 1998;179:421-9.

Alanen KW, Elit LM, Molinaro PA, McLachlin CM. Assessment of cytologic follow-up as the recommended management for patients with atypical squamous cells of undetermined significance or low grade squamous intraepithelial lesions. Cancer 1998;84:5-10.

Janicek MF, Averette HE. Cervical cancer: Prevention, Diagnosis and Therapeutics. CA Cancer J Clin 2001;51:92-114.

Richart RM. A modified terminology for cervical intraepithelial neoplasia. Obstet Gynecol 1990;75:131-3.

Solomon D, Davey D, Kurman R et al. The 2001 Bethesda System. Terminology for reporting results of cervical cytology. JAMA 2002; 287:2114-9.

Montz FJ. Management of high-grade cervical intraepithelial neoplasia and low-grade squamous intraepithelial lesion and potential complications. Clinical Obstetrics and Gynecology 2000;43:395-409.

Kaufman RH, Adam E, Vonka V. Human papillomavirus infection and cervical carcinoma. Clinical Obstetrics and Gynecology 2000;43:363-78.

Austoker J. Cancer Prevention in Primary Care: Screening for cervical cancer. BMJ 1994;309:241-8.

How to Cite

1.
González Mariño MA. Cervical pathology and reporting of atypical squamous cells of undetermined significance (ASCUS) in cervical cytology. Rev. colomb. obstet. ginecol. [Internet]. 2003 Jun. 30 [cited 2024 May 17];54(3):193-8. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/582

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Published

2003-06-30
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