A cohort study of the impact of a diagnosis of cervical dysplasia and human papilloma virus infection on the sexual functioning of females in a second-level hospital in Bogotá, Colombia
DOI:
https://doi.org/10.18597/rcog.252Keywords:
HPV infection, cervical dysplasia, sexual dysfunctionAbstract
Introduction: human papilloma virus (HPV) has gained importance due to the advent of molecular detection techniques allowing it to be identified before causing injury to the cervical epithelium. HPV infection means increased risk of cervical cancer as it is recognized as being a necessary cause of cervical cancer. This study was aimed at determining the impact of having a diagnosis of HPV, with or without dysplasia, on females's sexual functioning.
Materials and methods: cohort study designed to evaluate sexual functioning applying the Changes in Sexual Functioning Questionnaire (CSFQ-F) to 134 females; 71 had HPV and 63 did not have it. The questionnaire was applied on entering the study and 6 weeks afterwards. A descriptive analysis was made of the variables and bivariate and multivariate analysis of variables of interest.
Results: the relative risk of sexual dysfunction in females suffering from HPV and/or cervical dysplasia was 4.4 (95%CI 1,617; 11,972). Dysfunction was documented from the first survey. There were no statistical differences between the first and second surveys.
Conclusions: HPV infection was identified as being a risk factor for female sexual dysfunction; however, complementary studies must be made for confirming such association.
Author Biographies
Marcela Celis-Amórtegui
Jorge Aldas-Gracia
Médico Psiquiatra. Epidemiólogo Clínico. Profesor Asistente, Facultad de Medicina, Universidad El Bosque. Bogotá (Colombia)
Félix Andrés Toro-Moreno
References
Lorincz AT, Richart RM. Human papillomavirus DNA testing as an adjunct to cytology in cervical screening programs. Arch Pathol Lab Med 2003;127:959-68.
Bosch FX, Lorincz A, Muñoz N, Meijer CJ, Shah KV. The causal relation between papillomavirus and cervical cancer. J Clin Pathol 2002;55:244-65.
Bosch FX, Cuzick J. Chapter 30: HPV vaccines and screening in the prevention of cervical cancer. Vaccine 2006;24:S3/251-61.
Franco EL, Duarte-Franco E, Ferenczy A. Cervical cancer: epidemiology, prevention and the role of human papillomavirus infection. CAMJ 2001;164:1017-25.
Trottier H, Franco EL The epidemiology of genital human papillomavirus infection. Vaccine 2006;24:S4-15.
Ho GYF, Bierman R, Beardsley L, Chang CJ, Burk RD. Naturalhistory of cervical papillomavirus infection in young women. N Engl J Med 1988;338:423-8.
Posso H, Wiesner C, Piñeros M, Murillo R, González M, Tovar S. Manual de Normas técnico administrativas de detección y control del cáncer de cuello uterino. Segunda edición. Bogotá: Secretaría de Salud, Alcaldía Mayor de Bogotá, INC; 2005.
Molano M, Poso H, Weiderpass E, van den Brule AJ, Ronderos M, Franceschi S, et al. Prevalence and determinants of HPV infection among Colombian women with normal cytology. Br J Cancer 2002;87:324-33.
Orellana C, Casado E, Masip M, Galisteo C, Gratacós J, Larrosa M. Sexual dysfunction in fibromyalgia patients. Clin Exp Rheumatol 2008;26:663-6.
Crespo Iglesias JM, Prado Robles V, Pérez García M. Assessing the sexual functioning of chronic inpatients at a psychosocial rehabilitation unit. Actas Esp Psiquiatr 2006;34:41-7.
Jones LR. The use of validated questionnaires to assess females sexual dysfunction. World J Urol 2002;20:89-92.
Dalpiaz O, Kerschbaumer A, Mitterberger M, Pinggera GM, Colleselli D, Bartsch G, et al. Female sexual dysfunction: a new urogynaecological research field. BJU Int 2008;101:717-21.
Singh JC, Tharyan P, Kekre NS, Singh G, Gopalakrishnan G. Prevalence and risk factors for female sexual dysfunction in women attending a medical clinic in South India. J Postgrad Med 2009;55:113-20.
Hullfish KL, Pastore LM, Mormon AJ, Wernecke Y, Bovbjerg VE, Clayton AH. Sexual functioning of Latino women seeking outpatient gynecologic care. J Sex Med 2009;6:61-9.
Graziottin A, Serafini A. HPV infection in women: psychosexual impact of genital warts and intraepithelial lesions. J Sex Med 2009;6:633-45.
Conaglen HM, Hughes R, Conaglen JV, Morgan J. A prospective study of the psychological impact on patients of first diagnosis of human papillomavirus. Int J STD AIDS 2001;12:651-8.
McCaffery KJ, Irwig L, Turner L, Chan SF, Macaskill P, Lewicka M. Psychosocial outcomes of three triage methods for the management of borderline abnormal cervical smears: anopenrandomized trial. BMJ2010; 340:b4491.
Meston CM, Derogatis LR. Validated instruments for assessing female sexual function. J Sex Marital Ther 2002;28 Suppl 1:155-64.
Clayton AH, McGarvey EL, Clavet GJ. The Changes in Sexual Functioning Questionnaire (CSFQ): development, reliability, and validity. Psychopharmacol Bull 1997;33:731-45.
Bobes J, Gonzalez MP, Rico-Villademoreos F, Bascaran MT, Sarasa P, Clayton A. Validation of the Spanish version of the Changes in Sexual Functioning Questionnaire-CSFQ. J Sex Marital Ther 2000;26:119-31.
Keller A, McGarvey EL, Clayton AH. Reliability and construct validity of the Changes in Sexual Functioning Questionnaire Short Form (CSFQ-14). J Sex Marital Ther 2006;32:43-52.
Clayton AH, McGarvey EL, Clavet GJ, Piazza L. Comparison of sexual functioning in clinical and nonclinical populations using the Changes in Sexual Functioning Questionnaire. Psychopharmacol Bull 1997;33:747-53.
Kitchener HC, Fletcher I, Roberts C, Wheeler P, Almonte M, Maguire P. The psychosocial impact of human papillomavirus testing in primary cervical screening-a study within a randomized trial. Int J Gynecol Cancer 2008;18:743-8.
McCaffery KJ, Irwig L, Turner R, Chan SF, Macaskill P, Lewicka M, et al. Psychosocial outcomes of three triage methods for the management of borderline abnormal cervical smears: an open randomised trial. BMJ 2010;340:b4491. doi: 10.1136/bmj.b4491
Maissi E, Marteau TM, Hankins M, Moss S, Legood R, Gray A. Psychological impact of human papillomavirus testing in women with borderline or mildly dyskaryotic cervical smear test results: cross sectional questionnaire study. BMJ 2004;328:1293.
McCaffery K,Waller J,Forrest S,Cadman L, Szarewski A, Wardle J. Testing positive for human papillomavirus in routine cervical screening: examination of psychosocial impact. BJOG 2004;111:1437-43.
Maissi E, Marteau TM, Hankins M, Moss S, Legood R, Gray A. The psychological impact of human papillomavirus testing in women with borderline or mildly dyskaryotic cervical smear test results: 6-month follow-up. Br J Cancer 2005;92:990-4.
Papa D, Moore Simas TA, Reynolds M, Melnitsky H. Assessing the role of education in women's knowledge and acceptance of adjunct high-risk human Papillomavirus testing for cervical cancer screening. J Low Genit Tract Dis 2009;13:66-71.
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