Umbilical cord pseudo-cysts: clinical case report and review of the literature

Authors

  • Johana Carolina Arango-Pineda
  • Diana Soley Olivares-Concha
  • María Fernanda Rojas-Salazar
  • Juan Carlos Quintero-Mejía
  • Wilmar Saldarriaga-Gil

DOI:

https://doi.org/10.18597/rcog.111

Keywords:

Umbilical cord, pseudocyst, cord cyst

Abstract

Introduction: Umbilical cord cysts are classified as pseudo-cysts and true cysts, the difference being the presence of epithelium inside the cyst on hystology. The objective of this paper is to report a case of umbilical cord pseudocyst in Colombia, and a review of the literature regarding its origin, diagnostic difference, and potential association with congenital abnormalities.

Materials and methods: 20 year-old female patient referred to the Valle University Hospital in Cali, a tertiary level institution. On ultrasound, multiple hypoechoic images were found in the proximal portion of the umbilical cord at 16 weeks. At 32 weeks, she was undergone to C-section due to pre-term labor and podalic presentation of a female newborn with no congenital abnormalities and 46, XX karyotype. The umbilical cord showed a hydropic appearance and, under the microscopic examination, 3 vessels were seen, accompanied by edema of Wharton’s jelly, mixoid changes and no epythelium. The final diagnosis was umbilical cord pseudocyst. A search of the literature was conducted in Medline, Ovid, ScienceDirect and Cochrane Reviews using the terms umbilical cord, pseudocyst, and umbilical cord cyst.

Conclusion: Umbilical cord pseudocysts and true cysts are of good prognosis when they are the only abnormal finding in the fetus, but there is an important association between cysts and other anatomical defects and chromosomal abnormalities.

Author Biographies

Johana Carolina Arango-Pineda

Residente de Ginecología y Obstetricia. Universidad del Valle. Hospital Universitario del Valle. Departamento de Ginecología y Obstetricia, Cali, Colombia.

Diana Soley Olivares-Concha

Residente de Ginecología y Obstetricia. Universidad del Valle. Hospital Universitario del Valle. Departamento de Ginecología y Obstetricia, Cali, Colombia.

María Fernanda Rojas-Salazar

Residente de Anatomía Patológica y Patología Clínica. Universidad del Valle. Hospital Universitario del Valle. Departamento de Patología, Cali, Colombia.

Juan Carlos Quintero-Mejía

Especialista en Ginecología y Obstetricia. Diagnóstico prenatal. Universidad del Valle. Hospital Universitario del Valle. Profesor Auxiliar, Departamento de Ginecología y Obstetricia, Cali, Colombia.

Wilmar Saldarriaga-Gil

Especialista en Ginecología y Obstetricia. Embriología-Genética. Profesor Asociado, Departamentos de: Ginecología y Obstetricia, Morfología. Hospital Universitario del Valle. Director del Programa Medicina y Cirugía. Universidad del Valle, Cali, Colombia.

References

Sepúlveda W, Gutiérrez J, Sánchez J, Be C, Schnapp C. Pseudocyst of the umbilical cord: prenatal sonographic appearance and clinical significance. Obstet Gynecol. 1999;93:377-81.

Ghezzi F, Raio L, Di Naro E, Franchi M, Cromi A, Durig P. Single and multiple umbilical cord cysts in early gestation: two different entities. Ultrasound Obstet Gynecol. 2003;21:215-9.

Ross J, Jurkovic D, Zosmer N, Jauniaux E, Hacket E, Nicolaides K. Umbilical cord cysts in early pregnancy. Obstet Gynecol. 1997;89:442-5.

Smith G, Walker M, Johnston S, Ash K. The sonographic finding of persistent umbilical cord cystic masses is associated with lethal aneuploidy and/or congenital anomalies. Prenat Diagn. 1996;16:1141-7.

Shipp T, Bromley B, Benacerraf B. Sonographically detected abnormalities of the umbilical cord. Int J Gynaecol Obstet 1995;48:179-85.

Kiran H, Kiran G, Kanber Y. Pseudocyst of the umbilical cord with mucoid degeneration of Wharton’s jelly. Eur J Obstet Gynecol Reprod Biol. 2003;111:91-3.

Zangen R, Boldes R, Yaffe H, Schwed P, Weiner Z. Umbilical cord cysts in the second and third trimesters: significance and prenatal approach. Ultrasound Obstet Gynecol 2010;36:296-301.

Kellow Z, Feldstein V. Ultrasound of the placenta and umbilical cord: a review. Ultrasound Q. 2011;27:187-97.

Emura T, Kanamori Y, Ito M, Tanaka Y, Hashizume K, Genzo M, et al. Marumo. Omphalocele associated with a large multilobular umbilical cord pseudocyst. Pediatr Surg Int. 2004;20:636-9.

Jauniaux E, Jurkovic D, Campbell S. Sonographic Pseudoquistes features of an umbilical cord abnormality combining a cord pseudocyst and a small omphalocele a case report. Eur J Obstet Gynaecol Reprod Biol. 1991;40:245-8.

Gilboa Y, Kivilevitch Z, Katorza E, Leshem Y, Borokovski T, Spira M, et al. Outcomes of Fetuses With Umbilical Cord Cysts Diagnosed During Nuchal Translucency Examination. J Ultrasound Med. 2011;30:1547-51.

Kilicdag B, Kilicdag H, Bagis T, Tarim E, Yanik F. Large pseudocyst of the umbilical cord associated with patent urachus. J Obstet Gynaecol Res. 2004;30:444-7.

Dudiak CM, Salomon CG, Posniak HV, Olson MC, Flisak ME. Sonography of the umbilical cord. Radiographics. 1995;15:1035-50.

Eggebø TM, Dirdal HU, Vonbrandis P. Allantoidcyst in the umbilical cord diagnosed with B-flow ultrasound. BMJ Case Rep. 2012; 2012.

Schiesser M, Lapaire O, Holzgreve W, Tercanli S. Umbilical cord edema associated with patent urachus. Ultrasound Obstet Gynecol. 2003;22:646-7.

Tazi F, Ahsaini M, Khalouk A, Mellas S, Stuurman- Wieringa RE, Elfassi MJ, et al. Abscess of urachal remnants presenting with acute abdomen: a case series. J Med Case Rep. 2012;30:226-6.

Bonilla F Jr, Raga F, Villalaiz E, Osborne N, Castillo JC, Bonilla-Musoles F. Umbilical cord cysts: evaluation with different 3-dimensional sonographic modes. J Ultrasound Med 2010;29:281-5.

Bulgan E, Kilicdag H, Bagis T, Tarim E, Yanik F. Large pseudocyst of the umbilical cord associated with patent urachus. J Obstet Gynaecol. 2004;30:444-7.

Alimoglu E, Simsek M, Ceken K, Mendilcioglu I, Kabaalioglu A, Sindel T. Umbilical cord pseudocyst in a fetus with Down syndrome. Prenat Diagn. 2006;2:193-4.

How to Cite

1.
Arango-Pineda JC, Olivares-Concha DS, Rojas-Salazar MF, Quintero-Mejía JC, Saldarriaga-Gil W. Umbilical cord pseudo-cysts: clinical case report and review of the literature. Rev. colomb. obstet. ginecol. [Internet]. 2013 Sep. 30 [cited 2024 May 18];64(3):344-9. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/111

Downloads

Download data is not yet available.

Published

2013-09-30
QR Code

Altmetric

Article metrics
Abstract views
Galley vies
PDF Views
HTML views
Other views