Trombosis mesentérica aguda en gestante con mutación de Factor V Leiden y antecedentes de fertilización in vitro y transferencia de embriones: reporte de caso y revisión de la literatura
DOI:
https://doi.org/10.18597/rcog.3854Palabras clave:
trombosis, embarazo, vena mesentérica, fertilización in vitro, deficiencia de factor VResumen
Objetivos: presentar el caso de una paciente diagnosticada con trombosis aguda de la vena mesentérica (TAVM) asociada a mutación de Factor V Leiden y antecedente de fertilización in vitro y transferencia de embriones, y hacer una revisión de la literatura sobre los factores de riesgo y los tratamientos realizados en los casos de TAVM.
Materiales y métodos: reporte de un caso de mujer gestante de 37 años. Se realizó una búsqueda bibliográfica en las bases de datos Medline/PubMed y LILACS, filtrando por idioma (inglés y español). Se incluyeron estudios de cohortes primarias, casos y controles, reportes de casos y series de casos que examinaran los factores de riesgo asociados con el desarrollo de trombosis mesentérica aguda durante el embarazo y los tratamientos realizados.
Resultados: se identificaron estudios de casos y controles, reportes de casos y series relacionados con isquemia mesentérica, embarazo y fertilización in vitro, y se encontró que los principales factores asociados con isquemia mesentérica son el embarazo mismo, factores genéticos, medicamentos, la deficiencia de proteína C y S, y causas idiopáticas.
Conclusiones: la trombosis de la vena mesentérica superior es una condición infrecuente que amenaza la vida y ocurre durante el embarazo. La literatura sugiere que, durante la gestación, los factores asociados con la trombosis mesentérica aguda son la hipercoagulabilidad inducida por el embarazo, la administración de estrógeno oral durante el proceso de fertilización in vitro y transferencia de embriones, y otros factores desencadenantes. Es necesario realizar más estudios para comprender mejor los posibles factores adicionales y desarrollar mejores algoritmos para un tratamiento óptimo.
Biografía del autor/a
Furkan Karahan, katip çelebi üniversty
IKCU Ataturk Training and Research Hospital, Department of General Surgery, İzmir (Turkey).
Arif Atay, IKCU Ataturk Training and Research Hospital, Department of General Surgery, İzmir (Turkey).
IKCU Ataturk Training and Research Hospital, Department of General Surgery, İzmir (Turkey).
Fatma Hüsniye Dilek, IKCU Ataturk Training and Research Hospital, Department of General Surgery and Medical Pathology, İzmir (Turkey).
IKCU Ataturk Training and Research Hospital, Department of General Surgery and Medical Pathology, İzmir (Turkey).
Cengiz Tavusbay, IKCU Ataturk Training and Research Hospital, Department of General Surgery and Medical Pathology, İzmir (Turkey).
IKCU Ataturk Training and Research Hospital, Department of General Surgery and Medical Pathology, İzmir (Turkey).
Murat Kemal Atahan, IKCU Ataturk Training and Research Hospital, Department of General Surgery, İzmir (Turkey).
IKCU Ataturk Training and Research Hospital, Department of General Surgery, İzmir (Turkey).
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