Uterine collision tumor. Case report and review of the literature
DOI:
https://doi.org/10.18597/rcog.4011Keywords:
Uterine neoplasms, uterine cervix neoplasms, endometrial neoplasms, neoplasms, uterusAbstract
Objectives: To report the case of a patient with a uterine collision tumor and to conduct a review of the literature.
Material and methods: A 76-year-old patient who presented to the national cancer referral center in Bogota (Colombia), where she was diagnosed with a uterine collision tumor consisting of a seroustype endometrial adenocarcinoma and a cervical adenosarcoma. The patient underwent surgical treatment followed by chemotherapy and supplemental radiotherapy, and died 16 months later. A search was conducted in the Medline via PubMed and Embase databases, including reports and case series of women with a diagnosis of uterine collision tumor, with retrieval of information regarding diagnosis, treatment and prognosis. A narrative summary of the findings was made.
Results: The search identified 36 titles, of which 14 studies with 17 patients were included. The most frequent histopathological diagnosis was endometrial adenocarcinoma and high and low grade endometrial sarcoma (47 %). Primary treatment was surgery and adjuvant treatment with chemotherapy and radiotherapy (15 %) was performed in close to 50 % of cases. One-year survival was 75 %.
Conclusions: No cases of uterine collision tumors with the histopathology or in the location of the reported case were found in the literature. If this reported case is taken into account, 2-year mortality is 28 %. Further studies to describe the immunohistochemistry, treatment and prognosis of this condition are needed.
Author Biographies
Franco Rafael Ruiz-Echeverría, Instituto Nacional de Cancerología, Bogotá (Colombia).
Fellow de Ginecología oncológica, Instituto Nacional de Cancerología, Universidad Militar Nueva Granada, Bogotá (Colombia).
María Islena Beltrán-Salazar, Instituto Nacional de Cancerología, Bogotá (Colombia).
Patóloga oncóloga, Instituto Nacional de Cancerología, Bogotá (Colombia).
Lina María Caicedo-Páez, Instituto Nacional de Cancerología, Bogotá (Colombia).
Ginecóloga oncóloga, Instituto Nacional de Cancerología, Bogotá (Colombia).
Maribel Palencia-Palacios, Instituto Nacional de Cancerología, Bogotá (Colombia).
Patóloga, Instituto Nacional de Cancerología, Bogotá (Colombia).
Catherin Salazar-Silva, Instituto Nacional de Cancerología, Bogotá (Colombia).
Fellow de Ginecología oncológica, Instituto Nacional de Cancerología, Universidad Militar Nueva Granada, Bogotá (Colombia).
David Viveros-Carreño, Instituto Nacional de Cancerología, Bogotá (Colombia).
Ginecólogo oncólogo, Instituto Nacional de Cancerología y Clínica Universitaria Colombia, Bogotá (Colombia).
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