Buschke-Lowenstein tumour: Case presentation and review of the literature
DOI:
https://doi.org/10.18597/rcog.369Keywords:
Buschke-Lowenstein tumour, condyloma acuminatum, verrucous carcinomaAbstract
Objective: To present the case of a patient with a Buschke-Lowenstein tumour, and to conduct a review of the literature on its diagnosis and treatment.
Materials and Methods: Case presentation of a 19 year-old female patient with a rapidly progressing vulvar giant condyloma or Buschke-Lowenstein tumour who underwent partial vulvectomy in a level III referral Hospital in Bogotá, Colombia. A review of the literature was conducted in the Medline databases via PubMed, EBSCO and ProQuest, and in SciELO, of articles published between 2000 and 2015, including review articles and case reports. The search covered articles published in English and Spanish using the MeSH terms giant condyloma and Buschke-Lowenstein.
Results: Overall, 26 titles were identified, of which 20 studies were included. Of these, 18 were case reports, 1 was a case series and 1 was a review article. Its origin is usually associated with HPV infection by serotypes 6 and 11, and there is a low risk of malignancy. Diagnosis is made on the basis of the clinical history and physical examination, although the histopathological diagnosis is the gold standard. Complete surgical resection of the lesion has been the treatment most widely used. There is no consistent information regarding disease-free time period.
Conclusion: The Buschke-Lowenstein tumour is an infrequent condition and the diagnostic approach requires a high degree of clinical suspicion. Treatment is based on complete resection of the lesion and is accompanied on occasions by the administration of adjuvant therapy in order to reduce the rate of recurrence. Further studies are needed on the diagnosis and treatment of this condition.
Author Biographies
María Camila Hernández-Tiria
Sonia Salamanca-Mora
Adriana Cruz-Garnica
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