Etiological prevalence of urinary tract infections in symptomatic pregnant women in a high complexity hospital in Medellín, Colombia, 2013-2015

Authors

DOI:

https://doi.org/10.18597/rcog.3332

Keywords:

Urinary infections, infectious complications of pregnancy, urinalysis

Abstract

Objective: To determine the prevalence of urinary tract infections (UTIs), the microbiological profile and antibiotic resistance in pregnant women with suspected urinary tract infection.

Materials and methods: Cross-sectional study of pregnant women with suspected community-acquired urinary tract infection referred to the outpatient clinic by prenatal care practitioners or seen in the emergency room, and hospitalized between August 2013 and September 2015 in a referral teaching hospital located in Medellin, Colombia. Pregnant women who had received antibiotics on the day before admission were excluded. Random sampling. Measured variables: sociodemographic, clinical and bacteriological. Descriptive statistics were applied.

Results: The prevalece of urinary tract infections was 29%. Gram negative bacteria isolates were found predominantly, the main ones being E. coli and K. pneumoniae at 57.7 and 11.4%, respectively. Resistance to trimethoprim- sulfamethoxazole and to ampicillin-sulbactam was observed in 19.5% and 17.5% of isolates, respectively.

Conclusions: Population-based studies are needed to provide a better approach to bacterial resistance in community-acquired UTIs. On the other hand, the high resistance observed may suggest that some of the exposed antibiotics might not be included in the local guidelines for the management of UTIs.

Author Biographies

Daniel Sanín-Ramírez, Universidad Pontificia Bolivariana

Médico general, Universidad CES; residente de Ginecología y Obstetricia, Universidad Pontificia Bolivariana, Medellín (Colombia).

Cristian Calle-Meneses, Universidad Pontificia Bolivariana

Médico general, Universidad Pontificia Bolivariana, UT San Vicente CES, Medellín (Colombia).

Carolina Jaramillo-Mesa, Universidad Pontificia Bolivariana

Médico general, Universidad Pontificia Bolivariana, DAVITA, Medellín (Colombia).

Julián Alfredo Nieto-Restrepo, Universidad Pontificia Bolivariana

Médico general, Universidad Pontificia Bolivariana, SURA, Medellín (Colombia).

Diana Marcela Marín-Pineda, Universidad Pontificia Bolivariana

Estadística; Msc en Estadística; estudiante doctorado en Ciencias Médicas. Profesora asociada, Universidad Pontificia Bolivariana, Medellín (Colombia).

María Nazareth Campo-Campo, Universidad Pontificia Bolivariana

Especialista en Ginecología y Obstetricia, Universidad Pontificia Bolivariana; Subespecialista en Medicina Materno-Fetal, Universidad Autónoma de Barcelona; Clínica Universitaria Bolivariana, Medellín (Colombia).

References

Geerlings SE. Clinical Presentations and Epidemiology of Urinary Tract Infections. Microbiol Spectr. 2016;4(5)

https://doi.org/10.1128/microbiolspec.UTI-0002-2012

Whalley P. Bacteriuria of pregnancy. Am J Obstet Gynecol. 1967;97:723-38.

https://doi.org/10.1016/0002-9378(67)90458-9

Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM, et al. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis. 2005;40(5):643-54.

https://doi.org/10.1086/427507

Schnarr J, Smaill F. Asymptomatic bacteriuria and symptomatic urinary tract infections in pregnancy. Eur J Clin Invest. 2008;38 Suppl 2:50-7.

https://doi.org/10.1111/j.1365-2362.2008.02009.x

Schieve LA, Handler A, Hershow R, Persky V, Davis F. Urinary tract infection during pregnancy: Its association with maternal morbidity and perinatal outcome. Am J Public Health 1994;84:405-10.

https://doi.org/10.2105/AJPH.84.3.405

Smaill FM, Vazquez JC. Antibiotics for asymptomatic bacteriuria in pregnancy. Cochrane Database Syst Rev. 2015; 8):CD000490.

https://doi.org/10.1002/14651858.CD000490.pub3

Golan A, Wexler S, Amit A, Gordon D, David MP. Asymptomatic bacteriuria in normal and high-risk pregnancy. Eur J Obstet Gynecol Reprod Biol. 1989;33(2):101-8.

https://doi.org/10.1016/0028-2243(89)90202

Harris RE, Gilstrap LC 3rd. Cystitis during pregnancy: A distinct clinical entity. Obstet Gynecol. 1981;57(5):578-580.

Wing DA, Fassett MJ, Getahun D. Acute pyelonephritis in pregnancy: An 18-year retrospective analysis. Am J Obstet Gynecol. 2014;210(3):219.e1-219.e2196.

https://doi.org/10.1016/j.ajog.2013.10.006

Glaser AP, Schaeffer AJ. Urinar y tract infection and bacteriuria in pregnancy. Urol Cl in North Am. 2015;42(4):547-60.

https://doi.org/10.1016/j.ucl.2015.05.004

Martínez E, Osorio J, Delgado J, Esparza GE, Motoa G, Blanco VM, et al. Infecciones del tracto urinario bajo en adultos y embarazadas: consenso para el manejo empírico. Infectio. 2013;17(3):122-35

https://doi.org/10.1016/S0123-9392(13)70719-7

Campo-Urbina ML, Ortega-Ariza N, Parody-Muñoz A, Gómez-Rodríguez LC. Caracterización y perfil de susceptibilidad de uropatógenos asociados a la presencia de bacteriuria asintomática en gestantes del departamento del Atlántico, Colombia, 2014-2015. Estudio de corte transversal. Rev Colomb. Obstet Ginecol. 2017;68(1):62-70. Disponible en: http://www.scielo.org.co/pdf/rcog/v68n1/v68n1a06.pdf

https://doi.org/10.18597/rcog.2981

Gómez Bossa MA, Herrera Méndez M. Resistencia bacteriana en urocultivos de una población de embarazadas de control prenatal en Bogotá junio 2013-junio 2015. Biociencias. 2018;13:111-24.

Disponible en: https://revistas.unilibre.edu.co/index.php/biociencias/article/view/5003/4273

https://doi.org/10.18041/2390-0512/biociencias.2.5003

Orrego-Marin CP, Henao-Mejía CP, Cardona-Arias JA. Prevalencia de infección urinaria, uropatógenos y perfil de suceptibilidad antimicrobiana. Acta Med Colomb. 2014;39(4):352-8.

Ministerio de Salud y Protección Social Colombia - Colciencias. Guía de Práctica Clínica para la prevención, detección temprana y tratamiento del embarazo, parto o puerperio. Guías 11-15. Bogotá; 2013.

Allen VM, Yudin MH; Infectious Diseases Committee. Management of group B streptococcal bacteriuria in pregnancy. J Obstet Gynaecol Can. 2012;34(5):482-6.

https://doi.org/10.1016/S1701-2163(16)35246-X

Arroyave V, Cardona AF, Castaño-Castrillon JJ, Giraldo V, Jaramillo M, Moncada NC et al. Caracterización de la infección de las vías urinarias en mujeres embarazadas atendidas en una entidad de primer nivel de atención (Manizales, Colombia), 2006-2010. Arch Med. 2011;11(1):39-50. Disponible en: https://www.redalyc.org/pdf/2738/273819434003.pdf

https://doi.org/10.30554/archmed.11.1.1249.2011

Quiroga G, Robles R, Ruelas A, Gómez A. Bacteriuria asintomática en mujeres embarazadas, una amenaza subestimada. Rev Med Inst Mex Seguro Soc. 2007;45(2):169-72. Disponible en: https://www.medigraphic.com/pdfs/imss/im-2007/im072j.pdf

Abarzúa F, Zajer C, Donoso B, Belmar C, Riveros JP, González P. Reevaluación de la sensibilidad antimicrobiana de patógenos urinarios en el embarazo. Rev Chil Obstet Ginecol 2002;67(3):226-31. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0717-75262002000300011

https://doi.org/10.4067/S0717-75262002000300011

Casas PR, Ortiz M, Erazo-Bucheli D. Prevalencia de la resistencia a la ampicilina en gestantes con infección urinaria en el hospital universitario San José de Popayán (Colombia), 2007-2008. Rev Colomb Obstet Ginecol. 2009;60(4): 334-8. Disponible en: http://www.scielo.org.co/pdf/rcog/v60n4/v60n4a04.pdf

Schenkel DF, Dallé J, Antonello VS. Prevalência de uropatógenos e sensibilidade antimicrobiana em uroculturas de gestantes do Sul do Brasil. Rev Bras Ginecol Obstet. 2014;36(3):102-6. Disponible en: http://www.scielo.br/scielo.php?pid=S0100-72032014000300102&script=sci abstract&tlng=pt.

https://doi.org/10.1590/S0100-72032014000300002

Ferreira FE, Olaya SX, Zúñiga P, Angulo M. Infección urinaria durante el embarazo, perfil de resistencia bacteriana al tratamiento en el Hospital General de Neiva, Colombia. Rev Colomb Obstet Ginecol. 2005;56(3):239-43. Disponible en: https://revista.fecolsog.org/index.php/rcog/article/view/532/579

How to Cite

1.
Sanín-Ramírez D, Calle-Meneses C, Jaramillo-Mesa C, Nieto-Restrepo JA, Marín-Pineda DM, Campo-Campo MN. Etiological prevalence of urinary tract infections in symptomatic pregnant women in a high complexity hospital in Medellín, Colombia, 2013-2015. Rev. colomb. obstet. ginecol. [Internet]. 2019 Dec. 30 [cited 2024 May 18];70(4):243-52. Available from: https://revista.fecolsog.org/index.php/rcog/article/view/3332

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Published

2019-12-30

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