Prevalence of congenital defects in a third level hospital of Cali, Colombia 2004-2008. Association with maternal age
DOI:
https://doi.org/10.18597/rcog.233Keywords:
congenital defects, maternal age, genetic counselingAbstract
Objetive: to evaluate the association between maternal age and prevalence of congenital defects (CD) in a third level hospital in Cali, Colombia.
Materials and methods: cross-sectional study was developed based on data collected by the CD system records the Hospital Universitario del Valle (HUV), Cali, Colombia, between 2004 and 2008. It included all births in the period and determined the type of CD, socio-demographic variables of mothers. Prevalence according to maternal age and analyzed the association between maternal age and CD.
Results: during the study period 32 995 newborns were registered with an overall CD prevalence of 2.22%. We found a 4.5/1000 prevalence of vascular disruption defects (VDD) in mothers <15 years, and a 13.1/1000 prevalence of chromosomal defects in mothers >45 years.
Conclusions: as compared with the overall prevalence of CD, maternal age <20 is associated with a higher occurrence of VDD (3 to 4 times higher) while age >35 is related to chromosomal defects (13 times higher occurrence).
Author Biographies
Harry Pachajoa
Carlos Alberto Caicedo
Wilmar Saldarriaga
Fabián Méndez
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