Immunohistochemistry in breast pathology. Differentiating complex benign and malign breast lesions: a case report and literature review
DOI:
https://doi.org/10.18597/rcog.219Keywords:
imunohistochemistry of the breast, sclerosing adenosis, breast lesionsAbstract
Objective: reviewing the histological basis and differential diagnostic criteria for applying immunohistochemistry in breast pathology.
Clinical case: the case of a patient suffering from complex sclerosing lesion (CSL) of the breast, microglandular adenosis (MGA) pattern is presented; she required immunohistochemistry as an auxiliary technique for differentiating an adenocarcinoma-related breast lesion in situ and thus defining its treatment.
Materials and methods: a search was made of the pertinent information in Medline databases via PubMed, SciELO and in books on the specialty; 25 titles were reported, 12 of them corresponding to the immediate topic: 4 were case reports with a literature review and one was a letter to the editor. 7 articles dealt with the topic in a more general way.
Conclusion: immunohistochemistry led to the differential diagnosis of complex breast lesions such as sclerosing adenosis, and in situ or microinvase breast cancer.
Author Biographies
Omaira del Socorro Herrera-Arias
Jaime Díaz-Cardona
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