Autoinmunidad en pacientes con pérdida recurrente del embarazo

Francisco J. Espinel, Julio C. Mendoza, Jeannette Cubillos, Emilce Botero

Resumen


Un grupo de 90 mujeres con antecedente de 2 o más abortos espontáneos de causa desconocida, sin historia de partos anteriores, con estudio inmunológico que determinó ausencia de respuesta aloinmune y un grupo de control de 31 mujeres con antecedentede fertilidad comprobada, se estudiaron para anticuerpos a antígenos nucleares, anticoagulante lúpico y fosfolípidos. Demostramos serológicamente un incremento en la respuesta autoinmune a partir del segundo aborto. Los anticuerpos antifosfolípidos y los anticuerpos antinucleares aparecen presentes ya como epifenómenos ya como factores etiológicos en pacientes con pérdida recurrente del embarazo PRE.

La importancia de los hallazgos mencionados y la novedad del presente traba,jo consiste en la identificación del incremento en la respuesta autoinmune a partir del segundo aborto.


Palabras clave


Autoanticuerpos; abortadora primaria; fosfolípido; PRE pérdida recurrente del embarazo

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Referencias


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Este obra está bajo una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.

ISSN Impreso       0034-7434 

ISSN Electrónico   2463-0225

https://doi.org/10.18597/issn.0034-7434