Esteroides prenatales: ¿hora de redefinirlos?

  • Juan Carlos Sabogal

Resumen

La administración de Esteroides Prenatales (EP) con el fin de inducir la maduración pulmonar fetal ha sido una práctica aceptada durante los últimos 20 años, constituyéndose en una de las medidas prenatales más exitosas en términos de reducción de morbilidad y mortalidad perinatal secundaria a Síndrome de Dificultad Respiratoria Neonatal (SDRN). Reciente evidencia, asocia la administración de tales compuestos a diferentes efectos tanto fetales como maternos que suponen riesgos hasta el momento ignorados. Se revisa la literatura publicada en los últimos 6 años en lo referente a aspectos de dosificación, condiciones clínicas específicas (Ruptura prematura de membranas, recién nacido de muy bajo peso), así como las relaciones existentes entre los EP y ciertos desenlaces perinatales (hemorragia subaracnoidea, leucomalacia periventricular). Se concluye que es necesario redefinir sus indicaciones e individualizar su manejo en entornos clínicos específicos, mientras ensayos clínicos controlados que se llevan a cabo en este momento, permiten juicios sólidos.

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Biografía del autor/a

Juan Carlos Sabogal
Profesor Asistente, Facultad de Medicina, Departamento de Ginecobstetricia Universidad Nacional de Colombia. Instituto Materno Infantil. Unidad de Biología Reproductiva, Bogotá.

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Publicado
2001-09-28
Cómo citar
1.
Sabogal JC. Esteroides prenatales: ¿hora de redefinirlos?. Rev. Colomb. Obstet. Ginecol. [Internet]. 28 de septiembre de 2001 [citado 21 de octubre de 2021];52(3):235-41. Disponible en: https://revista.fecolsog.org/index.php/rcog/article/view/712
Sección
Revisión de Tema
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